Pubblicazioni scientifiche
di Federico Perna.

Ricerca collaborativa · Tumori del retto

A Prospective European Trial Comparing Laparotomy, Laparoscopy, Robotic-assisted, and Transanal Total Mesorectal Excision Procedures in High-risk Patients With Rectal Cancer: The RESET Trial

Rouanet P, Guerrieri M, Lemercier P, Balik E, Cotte E, Spinelli A, et al.; RESET Study Group. Ann Surg. 2026;283(4):697-706. Federico Perna figura tra i collaboratori. Pubblicato online nel 2024.

Leggi su PubMed: A Prospective European Trial Comparing Laparotomy, Laparoscopy, Robotic-assisted, and Transanal Total Mesorectal Excision Procedures in High-risk Patients With Rectal Cancer: The RESET Trial (si apre in una nuova scheda)

Malattie infiammatorie intestinali

Risk factors for early postoperative complications after minimally invasive surgery in pediatric ulcerative colitis

Di Benedetto M, Scarallo L, Renzo S, Naldini S, Paci M, Barp J, et al. J Pediatr Gastroenterol Nutr. 2026;82(4):1040-1050. Federico Perna tra gli autori.

Leggi su PubMed: Risk factors for early postoperative complications after minimally invasive surgery in pediatric ulcerative colitis (si apre in una nuova scheda)

Ricerca collaborativa · Chirurgia colorettale

Relationship between anastomotic technique, incisional hernia, and quality of life-the Minimally Invasive Right Colectomy Anastomosis STudy (MIRCAST)

Gómez Ruiz M; MIRCAST study group (collaborative). Br J Surg. 2025;112(12):znaf250. Federico Perna figura tra i collaboratori.

Leggi su PubMed: Relationship between anastomotic technique, incisional hernia, and quality of life-the Minimally Invasive Right Colectomy Anastomosis STudy (MIRCAST) (si apre in una nuova scheda)

Ricerca collaborativa

Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study

Bracale U, Podda M, Castiglioni S, Peltrini R, Sartori A, Arezzo A, et al.; CLOUD-19 Collaborative Group. Updates Surg. 2021;73(2):731-744. Federico Perna figura tra i collaboratori.

Leggi su PubMed: Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study (si apre in una nuova scheda)

Correzione editoriale · 2021: Correction to: Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study (si apre in una nuova scheda)

Chirurgia robotica e colorettale

Average treatment effect of robotic versus laparoscopic rectal surgery for rectal cancer

Solaini L, Perna F, Cavaliere D, Vaccaro C, Avanzolini A, Cucchetti A, et al. Int J Med Robot. 2021;17(2):e2210.

Leggi su PubMed: Average treatment effect of robotic versus laparoscopic rectal surgery for rectal cancer (si apre in una nuova scheda)

Recupero dopo chirurgia colorettale

The role of tibial nerve stimulation for enhanced postoperative recovery after colorectal surgery: a double-blind, parallel-group, randomized controlled trial

Martellucci J, Sturiale A, Alemanno G, Bartolini I, Pesi B, Perna F, et al. Tech Coloproctol. 2021;25(2):195-203.

Leggi su PubMed: The role of tibial nerve stimulation for enhanced postoperative recovery after colorectal surgery: a double-blind, parallel-group, randomized controlled trial (si apre in una nuova scheda)

Tumori del retto · Protocollo di studio

Expression levels of circulating miRNAs as biomarkers during multimodal treatment of rectal cancer - TiMiSNAR-mirna: a substudy of the TiMiSNAR Trial (NCT03962088)

Monsellato I, Garibaldi E, Cassinotti E, Baldari L, Boni L, Elmore U, et al. Trials. 2020;21(1):678. Federico Perna tra gli autori. Protocollo di studio.

Leggi su PubMed: Expression levels of circulating miRNAs as biomarkers during multimodal treatment of rectal cancer - TiMiSNAR-mirna: a substudy of the TiMiSNAR Trial (NCT03962088) (si apre in una nuova scheda)

Tumori del retto · Protocollo di studio

Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: a multicenter randomized controlled parallel group trial (TiMiSNAR)

Monsellato I, Alongi F, Bertocchi E, Gori S, Ruffo G, Cassinotti E, et al. BMC Cancer. 2019;19(1):1215. Federico Perna tra gli autori. Protocollo di studio.

Leggi su PubMed: Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: a multicenter randomized controlled parallel group trial (TiMiSNAR) (si apre in una nuova scheda)

Correzione editoriale · 2020: Correction to: Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: a multicenter randomized controlled parallel group trial (TiMiSNAR) (si apre in una nuova scheda)

Chirurgia colorettale

The use of intra-abdominal drain in minimally invasive right colectomy: a propensity score matched analysis on postoperative outcomes

Solaini L, Cavaliere D, Pecchini F, Perna F, Avanzolini A, Vitali G, et al. Int J Colorectal Dis. 2019;34(12):2137-2141.

Leggi su PubMed: The use of intra-abdominal drain in minimally invasive right colectomy: a propensity score matched analysis on postoperative outcomes (si apre in una nuova scheda)

Chirurgia robotica e colorettale

Robotic versus laparoscopic right colectomy with intracorporeal anastomosis: a multicenter comparative analysis on short-term outcomes

Solaini L, Cavaliere D, Pecchini F, Perna F, Bazzocchi F, Avanzolini A, et al. Surg Endosc. 2019;33(6):1898-1902.

Leggi su PubMed: Robotic versus laparoscopic right colectomy with intracorporeal anastomosis: a multicenter comparative analysis on short-term outcomes (si apre in una nuova scheda)

Oncologia · Caso clinico

Primary jejunal interdigitating dendritic cell sarcoma

Guerra F, Vegni A, Perna F, Messerini L, Coratti A. Ann Diagn Pathol. 2018;32:1-3.

Leggi su PubMed: Primary jejunal interdigitating dendritic cell sarcoma (si apre in una nuova scheda)

Chirurgia robotica

Robotic Rectal Resection With a Single-docking Technique Thanks to the Rotation of the R3 Arm

Pesi B, Annecchiarico M, Amore Bonapasta S, Nerini A, Perna F, Bencini L, et al. Surg Laparosc Endosc Percutan Tech. 2017;27(2):e18-e21.

Leggi su PubMed: Robotic Rectal Resection With a Single-docking Technique Thanks to the Rotation of the R3 Arm (si apre in una nuova scheda)

Chirurgia robotica e colorettale

Does robotics improve minimally invasive rectal surgery? Functional and oncological implications

Guerra F, Pesi B, Amore Bonapasta S, Perna F, Di Marino M, Annecchiarico M, et al. J Dig Dis. 2016;17(2):88-94.

Leggi su PubMed: Does robotics improve minimally invasive rectal surgery? Functional and oncological implications (si apre in una nuova scheda)

Chirurgia robotica del pancreas

Robotic pylorus-preserving pancreaticoduodenectomy: Technical considerations

Parisi A, Desiderio J, Trastulli S, Cirocchi R, Renzi C, Boselli C, et al. Int J Surg. 2015;21 Suppl 1:S59-63. Federico Perna tra gli autori.

Leggi su PubMed: Robotic pylorus-preserving pancreaticoduodenectomy: Technical considerations (si apre in una nuova scheda)

Chirurgia robotica del pancreas · Revisione sistematica

Challenges in robotic distal pancreatectomy: systematic review of current practice

Guerra F, Pesi B, Amore Bonapasta S, Di Marino M, Perna F, Annecchiarico M, et al. Minerva Chir. 2015;70(4):241-7.

Leggi su PubMed: Challenges in robotic distal pancreatectomy: systematic review of current practice (si apre in una nuova scheda)

Ricerca sperimentale

Effects of hydrogen sulfide (H2S) on mesenteric perfusion in experimental induced intestinal ischemia in a porcine model

Pavoni V, Nicoletti P, Benemei S, Materazzi S, Perna F, Romagnoli S, et al. Heart Lung Vessel. 2015;7(3):231-7.

Leggi su PubMed: Effects of hydrogen sulfide (H2S) on mesenteric perfusion in experimental induced intestinal ischemia in a porcine model (si apre in una nuova scheda)

Chirurgia laparoscopica

Single access laparoscopic colorectal surgery: lights and shadows

Pignata G, Bracale U, Mijatovic S, Perna F, Lazzara F, Badessi F. Acta Chir Iugosl. 2012;59(2):71-4.

Leggi su PubMed: Single access laparoscopic colorectal surgery: lights and shadows (si apre in una nuova scheda)

Oncologia colorettale

Pathologic determinants of survival after resection of T3N0 (Stage IIA) colorectal cancer: proposal for a new prognostic model

Cianchi F, Messerini L, Comin CE, Boddi V, Perna F, Perigli G, et al. Dis Colon Rectum. 2007;50(9):1332-41.

Leggi su PubMed: Pathologic determinants of survival after resection of T3N0 (Stage IIA) colorectal cancer: proposal for a new prognostic model (si apre in una nuova scheda)

Ricerca sperimentale

Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells

Cianchi F, Cortesini C, Magnelli L, Fanti E, Papucci L, Schiavone N, et al. Mol Cancer Ther. 2006;5(11):2716-26. Federico Perna tra gli autori.

Leggi su PubMed: Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells (si apre in una nuova scheda)

Ricerca sperimentale

Prostaglandin E(2) correlates with histamine production in human colorectal cancer

Cianchi F, Cortesini C, Perna F, Fabbroni V, Uliva C, Fabrizi F, et al. Inflamm Res. 2006;55 Suppl 1:S81-2.

Leggi su PubMed: Prostaglandin E(2) correlates with histamine production in human colorectal cancer (si apre in una nuova scheda)

Proctologia

Descending perineum syndrome: are abdominal hysterectomy and bowel habits linked?

Pucciani F, Boni D, Perna F, Bassotti G, Bellini M. Dis Colon Rectum. 2005;48(11):2094-9.

Leggi su PubMed: Descending perineum syndrome: are abdominal hysterectomy and bowel habits linked? (si apre in una nuova scheda)

Ricerca sperimentale

The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer

Cianchi F, Cortesini C, Schiavone N, Perna F, Magnelli L, Fanti E, et al. Clin Cancer Res. 2005;11(19 Pt 1):6807-15.

Leggi su PubMed: The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer (si apre in una nuova scheda)

Ricerca sperimentale

Histamine and histidine decarboxylase up-regulation in colorectal cancer: correlation with tumor stage

Masini E, Fabbroni V, Giannini L, Vannacci A, Messerini L, Perna F, et al. Inflamm Res. 2005;54 Suppl 1:S80-1.

Leggi su PubMed: Histamine and histidine decarboxylase up-regulation in colorectal cancer: correlation with tumor stage (si apre in una nuova scheda)

Ricerca sperimentale

Molecular characterization of established human colon carcinoma cell lines (HCT-8) made resistant to 5-fluorouracil by different selection schedules

Tempestini A, Caciagli B, Morganti M, Witort E, Nobili S, Papucci L, et al. Oncol Res. 2005;16(3):143-56. Federico Perna tra gli autori.

Leggi su PubMed: Molecular characterization of established human colon carcinoma cell lines (HCT-8) made resistant to 5-fluorouracil by different selection schedules (si apre in una nuova scheda)

Ricerca sperimentale

Apoptosis shifts to necrosis via intermediate types of cell death by a mechanism depending on c-myc and bcl-2 expression

Papucci L, Formigli L, Schiavone N, Tani A, Donnini M, Lapucci A, et al. Cell Tissue Res. 2004;316(2):197-209. Federico Perna tra gli autori.

Leggi su PubMed: Apoptosis shifts to necrosis via intermediate types of cell death by a mechanism depending on c-myc and bcl-2 expression (si apre in una nuova scheda)

Ricerca sperimentale

Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer

Cianchi F, Cortesini C, Fantappiè O, Messerini L, Sardi I, Lasagna N, et al. Clin Cancer Res. 2004;10(8):2694-704. Federico Perna tra gli autori.

Leggi su PubMed: Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer (si apre in una nuova scheda)

Ricerca sperimentale

Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis

Cianchi F, Cortesini C, Fantappiè O, Messerini L, Schiavone N, Vannacci A, et al. Am J Pathol. 2003;162(3):793-801. Federico Perna tra gli autori.

Leggi su PubMed: Inducible nitric oxide synthase expression in human colorectal cancer: correlation with tumor angiogenesis (si apre in una nuova scheda)